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Squamous cell carcinoma of the uterus from the eatlas of pathology squamous cell carcinoma squamous cell carcinoma 8;a nest of squamous carcinoma with keratinized cells in the center mimicking keratinization at the surface of the tissue.
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)t83000m80703 pathweb's virtual museum home esynopsis of pathology eatlas of pathology squamous carcinoma of cervix etiology •human papillomavirus (hpv) particularly types 16,18,31,33,35 pathogenesis •integration into host genome of hpv with inactivation of p53 •area of active research epidemiology •sexually transmitted disease particularly affecting young women •increased in cigarette smokers •age peak at 40-45 but dropping •women who have never had a pap smear or have not had one in 5 years clinical •symptoms of vaginal bleeding (post-coital) and discharge •most neoplasms are found at stage i (confined to cervix) •spread is contiguous into paracervical tissues and/or proximal vagina (stage ii) to the pelvic sidewall and/or lower vagina (stage iii) or into rectal or bladder mucosa (stage iv) •death from hemorrhage, infection, or obstruction of ureters or bowel •treatment with surgery or radiation (stage i), radiation for later stages (+/-) chemotherapy visit national cancer institute for current treatment general gross description •usually fungating, may be ulcerated or infiltrative •cut surfaces gray white, hard, poorly circumscribed •necrosis and hemorrhage common general micro description •usually non-keratinizing or keratinizing, rarely small cell •sheets or nests with individually keratinized cells or pearls •round to oval nuclei, coarsely granular chromatin •prominent nucleoli reference • cotran rs, kumar v, robbins sl: robbins pathologic basis of disease. where can i buy viagra in pune
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1052-1053 current literature from pubmed at national library of medicine synopsis by: melinda sanders m.
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D. viagra bph insurance , uchc pathweb's virtual museum home esynopsis of pathology eatlas of pathol.
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